Investigating the causes and factors of eosinophilic esophagitis in veterans

Who could benefit from this research

What this research studies

This research focuses on eosinophilic esophagitis (EoE), a chronic condition affecting the esophagus, particularly among veterans. By utilizing a large cohort of veterans diagnosed with EoE, the study aims to analyze clinical, environmental, and genetic data to identify triggers and contributing factors to the disease. The research will leverage extensive databases from the Veterans Health Administration to ensure a robust analysis of the epidemiology of EoE. Patients will be monitored for various outcomes, including comorbidities and treatment responses, to enhance understanding of this rising condition.

Why it matters

Where this research is happening

• VA San Diego Healthcare System
  San Diego, United States Active

Researchers

• Principal investigator: Low, Eric Edison — VA San Diego Healthcare System
• Study coordinator: Low, Eric Edison

Related research

Other NIH-funded projects on the same topics.

• Esophageal antigen test-guided diet for eosinophilic esophagitis

  A small, patient-friendly diet approach using a new esophageal antibody test aims to help people with eosinophilic esophagitis identify foods to avoid without repeated invasive procedures.

  NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11445933

• Allergic eosinophilic esophagitis drives dysregulated innate immunity in esophageal fibroblasts

  This project studies why eosinophilic esophagitis, a chronic food allergy-related condition, causes lasting changes in the esophagus and how these changes could be treated to prevent scarring and complications.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11443932

• How environmental signals and a receptor may protect or worsen eosinophilic esophagitis

  A new NIH grant is exploring how the aryl hydrocarbon receptor (AHR) in the esophagus affects eosinophilic esophagitis (EoE) and how environmental factors might influence this condition.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11377324

• Toward personalized care for pediatric eosinophilic esophagitis using multimodal biomarkers

  A pediatric-focused study will combine biochemical, structural, and molecular signals from the esophagus to better tailor treatment for kids with eosinophilic esophagitis.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11365332

• Role of protective proteins in the esophagus to treat eosinophilic esophagitis

  A research project aims to understand how certain proteins protect or restore the esophageal lining in children with eosinophilic esophagitis and how this could lead to better long-lasting therapies.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11353961

• Role of 1q21 Genetic Variants in Eosinophilic Esophagitis

  This project looks at how genetic differences may make some people with allergies more likely to develop eosinophilic esophagitis (EoE).

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11353128

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.