Investigating the causes and effects of jaw joint disorders
Official title: Local and Systemic Multi-Omics of TMJ Disorders
Funded at University of California Los Angeles · NIH-11130014 · Data updated 2026-11-12
This study is looking at jaw pain from temporomandibular disorders (TMD) to find better ways to diagnose and treat it, by examining different biological markers in patients, so that those suffering from TMD can receive more personalized care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 17, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $587,428 |
| NIH project number | 4UH3DE032208-02 |
| Project ID | NIH-11130014 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals experiencing symptoms of temporomandibular disorders, particularly women of reproductive age.
✕Less likely to help
Patients with temporomandibular disorders that are not associated with systemic factors or those who do not meet the specific inclusion criteria may not benefit from this research.
What this research studies
This research focuses on temporomandibular disorders (TMD), which cause pain in the jaw and affect a significant portion of the population. By analyzing local and systemic biological markers and cellular interactions, the study aims to identify specific diagnostic criteria and treatment strategies for patients suffering from these disorders. The approach involves collecting and analyzing various biological samples to understand the underlying mechanisms of TMD and its associated conditions, such as headaches and fibromyalgia. Patients will be stratified based on their unique multi-omic profiles to tailor more effective treatment options.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and targeted treatments for patients with temporomandibular disorders.
How similar studies have gone: Previous research has shown promise in using multi-omic approaches to understand complex disorders, suggesting potential for success in this novel application.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Kapila, Sunil D — University of California Los Angeles
- Study coordinator: Kapila, Sunil D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.