Investigating the brain development of infants exposed to HIV in Malawi
Neurocognitive development of HIV-exposed and uninfected infants in Malawi
This study is looking at how being exposed to HIV before birth affects babies' brain development in Malawi, comparing those born to mothers with HIV to those born to mothers without it, and will follow the babies for five years to learn more about their growth and health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10845553 on NIH RePORTER |
What this research studies
This research focuses on understanding how being exposed to HIV in the womb affects the brain development of infants in Malawi. It involves screening pregnant women and enrolling infants to analyze their immune responses and neurocognitive development over time. The study compares infants born to HIV-infected mothers with those born to uninfected mothers, assessing various biological and psychosocial factors that may influence their development. By following these infants for five years, the research aims to provide insights into the long-term effects of HIV exposure on child development.
Who could benefit from this research
Good fit: Ideal candidates for this research include infants born to HIV-infected mothers and those born to uninfected mothers in Malawi.
Not a fit: Patients who are not infants or who are not born in the context of HIV exposure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved interventions and support for infants exposed to HIV, enhancing their neurocognitive outcomes.
How similar studies have performed: Previous research has indicated that understanding the impacts of in utero HIV exposure can lead to significant advancements in child health, suggesting this approach has potential for success.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Laufer, Miriam K. — University of Maryland Baltimore
- Study coordinator: Laufer, Miriam K.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.