Investigating the biological differences in Alzheimer's disease and related dementias
Biological heterogeneity in ADRD
This study is looking at the different biological factors that affect how Alzheimer's and related dementias progress, with the goal of finding better ways to understand and treat these conditions for people living with them.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10896946 on NIH RePORTER |
What this research studies
This research focuses on understanding the biological diversity in Alzheimer's disease and related dementias (ADRD) by exploring the underlying mechanisms and biological factors that influence disease progression. The study employs advanced technologies to analyze human subjects and their biospecimens, integrating genetic, cognitive, anatomical, and neuropathological data. By examining various biomarkers and their interactions, the research aims to improve the classification of different ADRD phenotypes, which could lead to more targeted treatments and interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or related dementias, particularly those who can provide biological samples and participate in cognitive assessments.
Not a fit: Patients with other forms of dementia unrelated to Alzheimer's or those who are unable to participate in the required assessments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment strategies for patients with Alzheimer's disease and related dementias.
How similar studies have performed: Previous research has shown promise in understanding biological heterogeneity in Alzheimer's disease, indicating that this approach could yield valuable insights.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Grabowski, Thomas J. — University of Washington
- Study coordinator: Grabowski, Thomas J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.