Investigating the best use of laser therapy for glaucoma treatment
Clarifying the Optimal Application of SLT Therapy (COAST) Trial
This study is looking at how to make laser treatment for open-angle glaucoma work better, so patients can rely less on daily eye drops and have a smoother experience with their care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10912676 on NIH RePORTER |
What this research studies
This research focuses on optimizing the application of selective laser trabeculoplasty (SLT) for managing open-angle glaucoma (OAG). It aims to determine the most effective dosing and frequency of SLT to improve patient outcomes and reduce reliance on daily medications. By comparing SLT to traditional medical therapies, the study seeks to establish SLT as a first-line treatment option, potentially leading to better adherence and fewer complications for patients. The research will involve patient participation to assess the effectiveness of different SLT treatment protocols.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with open-angle glaucoma who may benefit from laser therapy as a primary treatment.
Not a fit: Patients with glaucoma who are already effectively managed with current medical therapies or those who are not suitable candidates for laser treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for glaucoma patients, reducing the need for daily medications and enhancing overall eye health.
How similar studies have performed: Previous research has shown promising results with laser therapies for glaucoma, indicating that this approach may lead to significant advancements in treatment.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Wisniewski, Stephen R — University of Pittsburgh at Pittsburgh
- Study coordinator: Wisniewski, Stephen R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.