Investigating the best use of laser therapy for glaucoma treatment

Clarifying the Optimal Application of SLT Therapy (COAST)

['FUNDING_OTHER'] · WEST VIRGINIA UNIVERSITY · NIH-10912595

This study is looking at how well a special laser treatment called selective laser trabeculoplasty (SLT) works for people with open-angle glaucoma, to see if it can help reduce the need for daily eye drops and make it easier for patients to stick to their treatment plans.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorWEST VIRGINIA UNIVERSITY (nih funded)
Locations1 site (MORGANTOWN, UNITED STATES)
Trial IDNIH-10912595 on ClinicalTrials.gov

What this research studies

This research focuses on open-angle glaucoma (OAG) and explores the effectiveness of selective laser trabeculoplasty (SLT) as a primary treatment option. It aims to determine the optimal application of SLT therapy, particularly in terms of energy levels and frequency of treatment, to improve patient outcomes. By comparing SLT to traditional medical therapies, the study seeks to provide insights into how laser treatment can reduce the need for daily medications and enhance adherence among patients. The research will analyze data from previous trials and patient responses to establish best practices for SLT application.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with open-angle glaucoma who may benefit from laser therapy as a primary treatment.

Not a fit: Patients with glaucoma who are already effectively managed with medical therapy or those with advanced glaucoma requiring surgical intervention may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment protocols for glaucoma, potentially reducing the need for daily medications and enhancing patient quality of life.

How similar studies have performed: Previous research has shown promising results for SLT as a treatment for glaucoma, indicating that this approach could lead to significant advancements in patient care.

Where this research is happening

MORGANTOWN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.