NIH-funded research R01 grant

Investigating the best eating schedule for weight loss in adults with obesity

Official title: Effects of early vs. late time restricted eating vs. daily caloric restriction on weight loss and metabolic outcomes in adults with obesity

Funded at University of Colorado Denver · NIH-11017022 · Data updated 2026-11-12

This study is looking to find the best eating schedule to help adults who are overweight or obese lose weight, comparing it to the usual method of cutting calories, while also offering support to help everyone stick to their plans and feel healthier.

More Obesity research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver
NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project startApril 5, 2023
Project endJanuary 31, 2028
Funding year2025
Award (this year)$590,693
NIH project number5R01DK132372-03
Project IDNIH-11017022 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 21 and older who are struggling with obesity and are looking for effective weight loss strategies.

Less likely to help

Patients who are not overweight or obese may not benefit from this research.

What this research studies

This research aims to find the most effective time-restricted eating (TRE) schedule for weight loss in adults who are overweight or obese. Participants will be assigned to different eating windows and compared to those following daily caloric restriction, the current standard for weight loss. The study will also incorporate behavioral support to help participants adhere to their eating plans and improve their overall health outcomes. By evaluating these different approaches, the research seeks to provide more effective dietary options for managing obesity.

Why it matters

Potential benefit: If successful, this research could lead to more effective dietary strategies for weight loss and improved metabolic health in adults with obesity.

How similar studies have gone: While some studies have explored time-restricted eating, this research aims to address limitations in previous studies and provide a more rigorous evaluation of its effectiveness.

Where this research is happening

  • University of Colorado Denver
    Aurora, United States
    Active

Researchers

  • Principal investigator: Thomas, Elizabeth Anne — University of Colorado Denver
  • Study coordinator: Thomas, Elizabeth Anne

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.