Investigating T Cell Responses in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Official title: Altered T Cell Responses in Myalgic Enchephalomeylitis/Chronic Fatigue Syndrome (ME/CFS)
Funded at Univ of Massachusetts Med Sch Worcester · NIH-11044125 · Data updated 2026-11-12
This study is looking at how a type of immune cell called T cells behaves in people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) compared to healthy individuals, to help uncover clues about the condition and find better ways to treat it.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project start | March 8, 2021 |
| Project end | February 28, 2026 |
| Funding year | 2025 |
| Award (this year) | $474,267 |
| NIH project number | 5R01AI159314-05 |
| Project ID | NIH-11044125 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
✕Less likely to help
Patients with other chronic illnesses or those without a diagnosis of ME/CFS may not benefit from this research.
What this research studies
This research focuses on understanding how T cells, a type of immune cell, respond in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). The study examines the differences in T cell behavior between individuals with ME/CFS and healthy individuals, particularly looking at markers of T cell activation and exhaustion. By analyzing blood samples, researchers aim to identify specific patterns in T cell responses that may contribute to the symptoms of ME/CFS. This could lead to better understanding of the disease and potential new treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic methods and targeted therapies for patients with ME/CFS.
How similar studies have gone: Previous research has indicated alterations in immune responses in ME/CFS, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Univ of Massachusetts Med Sch Worcester
Worcester, United States Active
Researchers
- Principal investigator: Selin, Liisa Kaarina — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Selin, Liisa Kaarina
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.