Investigating symptoms and medication adherence in women with breast cancer
A Multi-omics Approach to Examine Symptoms and Medication Adherence in Women with Breast Cancer
This study is looking at why some women with breast cancer have a hard time sticking to their treatment with aromatase inhibitors, by exploring different biological factors like genetics and gut health, to help improve their care and support.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10886733 on NIH RePORTER |
What this research studies
This research focuses on understanding the symptoms experienced by women undergoing treatment for breast cancer, particularly those taking aromatase inhibitors. It employs a multi-omics approach, which means it will analyze various biological data types to uncover the reasons behind medication adherence issues. By examining factors such as genetics and the gastrointestinal microbiome, the study aims to identify why some women struggle to stick to their treatment plans. The goal is to better characterize the relationship between symptoms and adherence over time, ultimately improving patient care.
Who could benefit from this research
Good fit: Ideal candidates for this research are postmenopausal women diagnosed with hormone receptor-positive breast cancer who are prescribed aromatase inhibitors.
Not a fit: Patients who are not postmenopausal or those who are not prescribed aromatase inhibitors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment adherence and better health outcomes for women with breast cancer.
How similar studies have performed: Previous research has shown that multi-omics approaches can successfully uncover biological factors influencing treatment outcomes, suggesting potential for success in this study.
Where this research is happening
Cleveland, United States
- Case Western Reserve University — Cleveland, United States (Active)
Researchers
- Principal investigator: Mccall, Maura Kindelan — Case Western Reserve University
- Study coordinator: Mccall, Maura Kindelan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.