Investigating sodium levels and lymphatic function in lymphedema
Official title: Imaging sodium and lymphatics in lymphedema
Funded at University of Virginia · NIH-11264103 · Data updated 2026-11-12
This study is looking at how the lymphatic system helps control sodium levels in people with lymphedema, using special imaging techniques to see how well the lymphatic system clears sodium and reduces swelling, with the goal of finding better ways to track and treat this condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project start | January 25, 2025 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $450,927 |
| NIH project number | 7R01HL155523-05 |
| Project ID | NIH-11264103 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with lymphedema, particularly those with well-characterized lymphatic disease.
✕Less likely to help
Patients without lymphedema or those with other unrelated conditions may not benefit from this research.
What this research studies
This research focuses on understanding how the lymphatic system manages sodium levels in tissues, particularly in patients with lymphedema. Using advanced noninvasive imaging techniques, the study aims to identify how lymphatic clearance affects sodium storage and tissue swelling. By examining these mechanisms, the research seeks to develop new imaging biomarkers that can track the progression of lymphedema and the effectiveness of treatments. This could lead to better management strategies for patients suffering from this condition.
Why it matters
Potential benefit: If successful, this research could provide new insights and tools for effectively managing lymphedema, potentially improving patient outcomes.
How similar studies have gone: While the approach of using noninvasive imaging to study lymphatic function is innovative, similar methodologies have shown promise in related areas of research.
Where this research is happening
-
University of Virginia
Charlottesville, United States Active
Researchers
- Principal investigator: Crescenzi, Rachelle L — University of Virginia
- Study coordinator: Crescenzi, Rachelle L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.