Investigating sodium levels and lymphatic function in lymphedema
Imaging sodium and lymphatics in lymphedema
This study is looking at how the lymphatic system helps control sodium levels in people with lymphedema, using special imaging techniques to see how well the lymphatic system clears sodium and reduces swelling, with the goal of finding better ways to track and treat this condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-11264103 on NIH RePORTER |
What this research studies
This research focuses on understanding how the lymphatic system manages sodium levels in tissues, particularly in patients with lymphedema. Using advanced noninvasive imaging techniques, the study aims to identify how lymphatic clearance affects sodium storage and tissue swelling. By examining these mechanisms, the research seeks to develop new imaging biomarkers that can track the progression of lymphedema and the effectiveness of treatments. This could lead to better management strategies for patients suffering from this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with lymphedema, particularly those with well-characterized lymphatic disease.
Not a fit: Patients without lymphedema or those with other unrelated conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide new insights and tools for effectively managing lymphedema, potentially improving patient outcomes.
How similar studies have performed: While the approach of using noninvasive imaging to study lymphatic function is innovative, similar methodologies have shown promise in related areas of research.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Crescenzi, Rachelle L — University of Virginia
- Study coordinator: Crescenzi, Rachelle L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.