Investigating social reward therapy for reducing suicidality in older adults

Target Engagement During Social Reward Psychotherapy for Mid- and Late-Life Suicidality: A Precision Imaging Trial

NIH-funded research Weill Medical Coll of Cornell Univ · NIH-11078339

This study is looking at how feeling socially disconnected can lead to thoughts of suicide in adults aged 50-80 with depression, and it will test a new online therapy called Engage & Connect that helps people get more involved in enjoyable social activities.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWeill Medical Coll of Cornell Univ NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11078339 on NIH RePORTER

What this research studies

This research focuses on understanding how social disconnection contributes to suicidality in mid- and late-life adults. It involves a novel psychotherapy called Engage & Connect, which is delivered remotely and aims to enhance engagement in rewarding social activities. The study will include 128 participants aged 50-80 with major depressive disorder and suicidal thoughts, who will be randomly assigned to either the therapy or an active control group. Researchers will assess brain functions and behavioral changes related to social rewards to evaluate the effectiveness of the intervention.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 50-80 who are experiencing major depressive disorder and have suicidal ideation.

Not a fit: Patients outside the age range of 50-80 or those without major depressive disorder or suicidal thoughts may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new therapeutic approach to reduce suicidality and improve mental health outcomes in older adults.

How similar studies have performed: Previous research has shown promise in using social engagement therapies to improve mental health outcomes, suggesting potential success for this novel approach.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.