Investigating small molecule signaling in a model organism related to human biology
Small Molecule Signaling in Caenorhabditis elegans
['FUNDING_OTHER'] · BOYCE THOMPSON INST FOR PLANT RESEARCH · NIH-11013356
This study is looking at tiny worms to see how certain small molecules can affect their growth, aging, and ability to handle stress, which might help us understand similar processes in humans and improve our knowledge of age-related health issues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOYCE THOMPSON INST FOR PLANT RESEARCH (nih funded) |
| Locations | 1 site (ITHACA, UNITED STATES) |
| Trial ID | NIH-11013356 on ClinicalTrials.gov |
What this research studies
This research focuses on the nematode Caenorhabditis elegans, a key model organism in biomedical research, to explore how small molecules influence various biological processes such as development, aging, and stress resistance. By characterizing the metabolome of C. elegans, the study aims to uncover the complex signaling pathways that are conserved in humans. The research will investigate the biosynthesis and perception of newly identified small molecule signals, which could provide insights into how metabolism and signaling pathways interact to affect health and aging. This work may lead to a better understanding of the biological mechanisms that underlie age-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research are individuals interested in the biological mechanisms of aging and age-related conditions.
Not a fit: Patients with conditions unrelated to aging or metabolic signaling may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of aging and related health issues, potentially leading to new therapeutic strategies.
How similar studies have performed: Other research has shown success in using model organisms like C. elegans to uncover fundamental biological processes relevant to human health.
Where this research is happening
ITHACA, UNITED STATES
- BOYCE THOMPSON INST FOR PLANT RESEARCH — ITHACA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SCHROEDER, FRANK CLEMENS — BOYCE THOMPSON INST FOR PLANT RESEARCH
- Study coordinator: SCHROEDER, FRANK CLEMENS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.