Investigating sleep patterns to identify causes of excessive daytime sleepiness
Official title: The space-time organization of sleep oscillations as potential biomarker for hypersomnolence
Funded at Research Inst Nationwide Children's Hosp · NIH-10889257 · Data updated 2026-11-12
This study is looking at why some people feel extremely sleepy during the day by exploring how their brains behave while they sleep, which could help doctors find better ways to diagnose and treat this condition.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Inst Nationwide Children's Hosp NIH-funded |
| Lab location | 1 site (Columbus, United States) |
| Project start | July 17, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $120,715 |
| NIH project number | 5R21HL170255-02 |
| Project ID | NIH-10889257 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old experiencing excessive daytime sleepiness, regardless of whether it is linked to other medical conditions.
✕Less likely to help
Patients who do not experience excessive daytime sleepiness or those under 21 years old may not benefit from this research.
What this research studies
This research focuses on understanding hypersomnolence, or excessive daytime sleepiness, by examining the brain's sleep oscillations. Researchers will use advanced techniques to analyze the space-time organization of sleep rhythms, which may help identify reliable biomarkers for this condition. By studying the brain's electrical activity during sleep, the project aims to differentiate between various causes of hypersomnolence, leading to better diagnostic and therapeutic options for patients. The findings could enhance our understanding of sleep disorders and improve patient care.
Why it matters
Potential benefit: If successful, this research could lead to the development of reliable biomarkers for diagnosing excessive daytime sleepiness, improving treatment options for affected patients.
How similar studies have gone: Previous research has shown promise in using advanced EEG techniques to analyze sleep patterns, suggesting that this approach could yield valuable insights into sleep disorders.
Where this research is happening
-
Research Inst Nationwide Children's Hosp
Columbus, United States Active
Researchers
- Principal investigator: Malerba, Paola — Research Inst Nationwide Children's Hosp
- Study coordinator: Malerba, Paola
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.