Investigating sleep patterns to identify causes of excessive daytime sleepiness
The space-time organization of sleep oscillations as potential biomarker for hypersomnolence
This study is looking at why some people feel extremely sleepy during the day by exploring how their brains behave while they sleep, which could help doctors find better ways to diagnose and treat this condition.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Inst Nationwide Children's Hosp NIH-funded |
| Lab location | 1 site (Columbus, United States) |
| Project ID | NIH-10889257 on NIH RePORTER |
What this research studies
This research focuses on understanding hypersomnolence, or excessive daytime sleepiness, by examining the brain's sleep oscillations. Researchers will use advanced techniques to analyze the space-time organization of sleep rhythms, which may help identify reliable biomarkers for this condition. By studying the brain's electrical activity during sleep, the project aims to differentiate between various causes of hypersomnolence, leading to better diagnostic and therapeutic options for patients. The findings could enhance our understanding of sleep disorders and improve patient care.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old experiencing excessive daytime sleepiness, regardless of whether it is linked to other medical conditions.
Not a fit: Patients who do not experience excessive daytime sleepiness or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of reliable biomarkers for diagnosing excessive daytime sleepiness, improving treatment options for affected patients.
How similar studies have performed: Previous research has shown promise in using advanced EEG techniques to analyze sleep patterns, suggesting that this approach could yield valuable insights into sleep disorders.
Where this research is happening
Columbus, United States
- Research Inst Nationwide Children's Hosp — Columbus, United States (Active)
Researchers
- Principal investigator: Malerba, Paola — Research Inst Nationwide Children's Hosp
- Study coordinator: Malerba, Paola
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.