Investigating sleep and brain health in veterans with multiple injuries
Official title: Glymphatics Imaging to Probe Sleep in Veterans with the Polytrauma Clinical Triad (GLIMPSE-PCT)
Funded at Portland VA Medical Center · NIH-11111037 · Data updated 2026-11-12
This study is looking at how sleep problems affect veterans with brain injuries and other long-term health issues, and it aims to find ways to better understand and improve their sleep and brain health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Portland VA Medical Center NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | April 1, 2025 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| NIH project number | 1I01RX005371-01A1 |
| Project ID | NIH-11111037 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are veterans who have experienced traumatic brain injuries and exhibit symptoms of the polytrauma clinical triad, including sleep disturbances.
✕Less likely to help
Patients who do not have a history of traumatic brain injury or do not exhibit symptoms of the polytrauma clinical triad may not benefit from this research.
What this research studies
This research focuses on understanding how sleep disturbances affect veterans who have experienced traumatic brain injuries and other chronic conditions, known as the polytrauma clinical triad. By examining the glymphatic system, which is responsible for clearing waste from the brain during sleep, the study aims to identify potential biomarkers that could indicate the risk of neurodegeneration in these veterans. The research will involve advanced imaging techniques to assess the glymphatic function and its relationship with sleep quality and cognitive health. Ultimately, the goal is to improve the understanding of how sleep impacts the overall health of veterans suffering from these complex conditions.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment strategies for veterans suffering from sleep disturbances and related neurodegenerative risks.
How similar studies have gone: Previous research has shown promising results in understanding the glymphatic system's role in brain health, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Portland VA Medical Center
Portland, United States Active
Researchers
- Principal investigator: Elliott, Jonathan E — Portland VA Medical Center
- Study coordinator: Elliott, Jonathan E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.