Investigating skin damage related to implants and its effects
Damage Modeling and Vascular Imaging Correlation with Implant Induced Skin Necrosis
['FUNDING_R01'] · GEORGIA INSTITUTE OF TECHNOLOGY · NIH-11041085
This study is looking at how skin damage happens around implants used in facial surgeries, aiming to find better ways to prevent complications like infections and the need for more surgeries, so patients can have better healing and outcomes.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEORGIA INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-11041085 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding skin necrosis that occurs over implants used in facial and craniofacial reconstructions. It aims to quantify the vascular compromise and skin damage caused by high stress and compression, which can lead to severe complications such as infections and the need for additional surgeries. By employing advanced techniques like finite element modeling, photoacoustic tomography, and ultrasound elastography, the study seeks to correlate these measurements with actual skin damage in patients. The ultimate goal is to develop better methods to prevent skin dehiscence and improve outcomes for patients with implants.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals undergoing facial or craniofacial reconstruction involving implants, particularly those at risk for skin complications.
Not a fit: Patients who do not have implants or are not undergoing related surgical procedures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved surgical techniques and materials that reduce the risk of skin necrosis and enhance recovery for patients with implants.
How similar studies have performed: While the approach of using finite element modeling and imaging techniques is innovative, similar studies have shown promise in understanding tissue responses to implants.
Where this research is happening
ATLANTA, UNITED STATES
- GEORGIA INSTITUTE OF TECHNOLOGY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HOLLISTER, SCOTT J — GEORGIA INSTITUTE OF TECHNOLOGY
- Study coordinator: HOLLISTER, SCOTT J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.