Investigating similarities in matrisome molecules during diseases
Methods for measuring matrisome molecule similarity during disease processes
This study is looking at special molecules in the brain and other tissues to see how they change when people have diseases like neurological disorders and cancer, which could help doctors find better ways to diagnose and treat these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11043416 on NIH RePORTER |
What this research studies
This research focuses on developing advanced methods to analyze matrisome molecules, which are essential components of the extracellular matrix in the brain and other tissues. By utilizing techniques like liquid chromatography-mass spectrometry and bioinformatics, the research aims to understand how these molecules change during various diseases, including neurological disorders and cancer. Patients may benefit from insights gained into the molecular mechanisms of their conditions, potentially leading to improved diagnostic and therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with neurological disorders, such as neurodegenerative diseases, or cancers affecting the brain.
Not a fit: Patients with conditions unrelated to neurological diseases or cancers may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for patients with neurological diseases and cancers.
How similar studies have performed: Other research has shown promise in using similar analytical methods to study disease mechanisms, indicating a potential for success in this approach.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Zaia, Joseph — Boston University Medical Campus
- Study coordinator: Zaia, Joseph
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.