Investigating shared genetic factors in pediatric cancers
Genetic pleiotropy across pediatric cancers, and cancer-related outcomes
['FUNDING_R01'] · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · NIH-11090561
This study is looking at the genetic links between different types of childhood cancers to see how these shared genes might affect how kids respond to treatment, with the goal of finding better ways to help them.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (nih funded) |
| Locations | 1 site (MEMPHIS, UNITED STATES) |
| Trial ID | NIH-11090561 on ClinicalTrials.gov |
What this research studies
This research aims to explore the genetic connections among various types of pediatric cancers, focusing on how these shared genetic factors may influence cancer outcomes. By analyzing a large dataset of over 43,000 pediatric cancer cases, the study will utilize advanced genomic techniques to identify common genetic markers across more than 25 cancer subtypes. This comprehensive approach seeks to enhance our understanding of cancer predisposition and improve treatment strategies for affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research include children diagnosed with any type of cancer, particularly those under the age of 11.
Not a fit: Patients with adult-onset cancers or those not diagnosed with cancer may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved risk assessment and targeted therapies for children diagnosed with cancer.
How similar studies have performed: Previous research has shown success in identifying genetic factors in individual cancer types, but this study represents a novel approach by examining genetic pleiotropy across multiple pediatric cancers.
Where this research is happening
MEMPHIS, UNITED STATES
- ST. JUDE CHILDREN'S RESEARCH HOSPITAL — MEMPHIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, ZHAOMING — ST. JUDE CHILDREN'S RESEARCH HOSPITAL
- Study coordinator: WANG, ZHAOMING
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.