Investigating SCAMP3's role in aggressive breast cancer

Who could benefit from this research

What this research studies

This research focuses on understanding how SCAMP3, a protein found to be overexpressed in triple-negative breast cancer (TNBC), contributes to the disease's progression. By examining the molecular mechanisms behind SCAMP3's regulation of the epidermal growth factor receptor (EGFR) and its interaction with other signaling proteins, the study aims to identify potential new therapeutic targets. The approach involves detailed biological analyses to uncover how SCAMP3 influences cancer cell behavior, which could lead to improved treatment options for patients with TNBC.

Why it matters

Where this research is happening

• Universidad Central Del Caribe
  Bayamon, United States Active

Researchers

• Principal investigator: Suarez, Ivette — Universidad Central Del Caribe
• Study coordinator: Suarez, Ivette

Related research

Other NIH-funded projects on the same topics.

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• Dormancy in Triple-Negative Breast Cancer: How Liver and Skin Metastases Go Quiet or Reactivate

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  NIH research Massachusetts Institute of Technology · Cambridge, United States · NIH-11531542

• Rac-enhanced CAR-Macrophages against TNBC

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  NIH research University of Louisville · Louisville, United States · NIH-11520503

• A new peptide therapy to help treat metastatic triple-negative breast cancer

  A new peptide therapy called PEG-FUD is being tested to help treat metastatic triple-negative breast cancer by normalizing the tumor environment to improve treatment delivery.

  NIH research University of Wisconsin-Madison · Madison, United States · NIH-11453153

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.