Investigating RNA targeting in brain circuits related to memory
Official title: Analysis of RNAs targeted to the long-distance projections of ventral hippocampus
Funded at University of Florida · NIH-10994656 · Data updated 2026-11-12
This study is looking at how certain RNA molecules work in the brain's memory area to help us understand learning and memory better, which could eventually lead to new treatments for memory problems.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | December 5, 2023 |
| Project end | November 30, 2025 |
| Funding year | 2025 |
| Award (this year) | $205,275 |
| NIH project number | 5R21MH133252-02 |
| Project ID | NIH-10994656 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing memory impairments or disorders, as well as those interested in the biological mechanisms of learning and memory.
✕Less likely to help
Patients with no cognitive or memory-related issues may not receive direct benefits from this research.
What this research studies
This research focuses on developing new methods to analyze how specific RNAs are targeted within brain circuits, particularly in the ventral hippocampus, which is crucial for long-term memory storage. By improving the identification of RNAs in distinct subcellular compartments, the study aims to enhance our understanding of how these molecules contribute to memory processes. The researchers will utilize advanced techniques to study RNA localization in living organisms, including mice, to uncover the roles these RNAs play in learning and memory. This could lead to insights into memory disorders and potential therapeutic approaches.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating memory-related disorders.
How similar studies have gone: While the investigation of RNA targeting in memory is a developing field, previous studies have shown promise in understanding RNA localization and its implications for memory function.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Puthanveettil, Sathya — University of Florida
- Study coordinator: Puthanveettil, Sathya
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.