Investigating RNA communication in blood cell formation
Hematopoietic circRNA-mediated intercellular communication
This study is testing a new, gentle blood test that looks at RNA to check the health of your bone marrow, which is important for making blood cells, especially for people with lung cancer and other blood-related conditions, so you can avoid the discomfort of traditional bone marrow biopsies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10993653 on NIH RePORTER |
What this research studies
This research focuses on developing a non-invasive RNA liquid biopsy platform to assess the health of the bone marrow, which is crucial for blood cell formation. By analyzing cell-free RNA in blood plasma, the study aims to provide insights into various conditions affecting blood production, such as cancer and other hematological disorders. This approach seeks to replace traditional bone marrow biopsies, which can be painful and carry risks, with a safer and more efficient method for monitoring blood health. The research will involve a cohort of lung adenocarcinoma patients to evaluate the effectiveness of this new diagnostic tool.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients with lung adenocarcinoma and those experiencing issues related to blood cell formation.
Not a fit: Patients who do not have blood-related conditions or are not undergoing treatment for lung adenocarcinoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more accurate methods for monitoring blood health and diagnosing related conditions.
How similar studies have performed: Previous research has shown promise in using RNA liquid biopsies for diagnostic purposes, indicating potential success for this novel approach.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Reggiardo, Roman E — Stanford University
- Study coordinator: Reggiardo, Roman E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.