Investigating risk factors for mild cognitive impairment and dementia in diverse seniors

Risk factors for MCI and Dementia in a Diverse Senior Cohort

['FUNDING_R01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10402922

This study is looking to learn more about what might increase or decrease the chances of seniors, especially those from low-income backgrounds, developing mild cognitive impairment or dementia, and it invites 800 older adults from certain neighborhoods to share their experiences and undergo regular check-ins to help us understand these important issues better.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded)
Locations1 site (PITTSBURGH, UNITED STATES)
Trial IDNIH-10402922 on ClinicalTrials.gov

What this research studies

This research focuses on understanding the risk factors associated with mild cognitive impairment (MCI) and dementia among a diverse group of seniors, particularly those from low-income backgrounds. By recruiting 800 seniors from specific boroughs with a high percentage of African American residents, the study aims to enhance existing data from a larger cohort study. Participants will undergo assessments to identify both risk and resilience factors related to cognitive decline, with follow-ups conducted annually to track changes over time. The research employs a community-based approach to ensure inclusivity and relevance to the populations studied.

Who could benefit from this research

Good fit: Ideal candidates for this research are seniors aged 60 and older, particularly those from low-income, minority backgrounds.

Not a fit: Patients who are not seniors or those who do not belong to the targeted low-income, minority groups may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention strategies for MCI and dementia, particularly in underrepresented communities.

How similar studies have performed: Previous research has shown success in understanding cognitive decline through community-based cohort studies, making this approach both relevant and promising.

Where this research is happening

PITTSBURGH, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.