Investigating retinal blood vessel changes in diabetes and hypertension
Assessment of Retinal Capillary Density, Morphology and Function in Retinal Vascular Disease Using Novel OCT Angiography Based Metrics
This study is looking at how diabetes and high blood pressure can impact the small blood vessels in your eyes, which might cause vision problems, and it uses a special imaging technique to spot early signs of these changes so that we can help you get better care sooner.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10916370 on NIH RePORTER |
What this research studies
This research focuses on understanding how diabetes and hypertension affect the tiny blood vessels in the retina, which can lead to vision loss. Using a non-invasive imaging technique called optical coherence tomography angiography (OCTA), the study aims to detect early changes in retinal capillaries that current methods often miss. By identifying these changes sooner, the research hopes to improve diagnosis and treatment options for patients with these conditions. The approach includes detailed assessments of capillary density and function to better understand the progression of retinal vascular diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults with diabetes or hypertension, particularly those at risk for retinal complications.
Not a fit: Patients without diabetes or hypertension, or those with advanced retinal disease already exhibiting significant vision loss, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and better management of retinal diseases, potentially preserving vision for many patients.
How similar studies have performed: Previous research using OCTA has shown promise in detecting retinal changes, suggesting that this approach could be effective in a clinical setting.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Kashani, Amir H — Johns Hopkins University
- Study coordinator: Kashani, Amir H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.