Investigating respiratory health in children with Down syndrome during the pandemic

Respiratory morbidity during the pandemic time in individuals with Down syndrome

NIH-funded research Vanderbilt University Medical Center · NIH-10916701

This study is looking at how the COVID-19 pandemic has impacted the breathing health of children with Down syndrome, and it aims to learn more about their experiences with respiratory infections and safety measures like wearing masks and social distancing.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center NIH-funded
Lab location1 site (Nashville, United States)
Project IDNIH-10916701 on NIH RePORTER

What this research studies

This research focuses on understanding how the COVID-19 pandemic has affected respiratory health in children with Down syndrome. By utilizing a large cohort of over 3,000 individuals with Down syndrome, the study aims to assess the respiratory morbidity experienced during this time. The research team will follow these individuals to gather data on respiratory infections and the impact of non-pharmaceutical interventions like social distancing and masking. This approach will help identify the unique vulnerabilities of this population and inform better health strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years with a diagnosis of Down syndrome.

Not a fit: Patients without Down syndrome or those outside the age range of 0-11 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved respiratory health management and preventive strategies for children with Down syndrome.

How similar studies have performed: Previous research has indicated that individuals with Down syndrome are at higher risk for severe respiratory infections, suggesting that this study's focus is both relevant and necessary.

Where this research is happening

Nashville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Airway infections
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.