Investigating proteins and genes related to Parkinson's disease
Multi-tissue High-throughput Proteomic and Genomic Study in Parkinson's Disease
This study is looking for clues in proteins and genes that could help us better understand Parkinson's disease, using samples from over 3,100 people, so we can improve how we diagnose and treat the condition for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10694843 on NIH RePORTER |
What this research studies
This research focuses on identifying potential biomarkers for Parkinson's disease (PD) by analyzing proteins and genes from various tissues, including cerebrospinal fluid and plasma. The study aims to overcome previous limitations by utilizing a large sample size of over 3,100 samples and employing advanced genomic and proteomic techniques. By comparing the biological data from clinically diagnosed PD patients and autopsy-confirmed cases, the research seeks to uncover molecular pathways associated with PD. Patients may benefit from improved diagnostic methods and targeted therapies based on the findings.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Parkinson's disease and those at risk due to genetic factors.
Not a fit: Patients with other neurodegenerative disorders or those without a diagnosis of Parkinson's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of reliable biomarkers for early diagnosis and treatment of Parkinson's disease.
How similar studies have performed: Previous research in other neurodegenerative diseases has successfully identified biomarkers using similar high-throughput genomic and proteomic approaches.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Benitez, Bruno a. — Beth Israel Deaconess Medical Center
- Study coordinator: Benitez, Bruno a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.