Investigating protein sequencing using advanced technologies

Single Molecule Protein Sequencing using Nanopores and Deep-UV Raman Spectroscopy

['FUNDING_R21'] · UNIVERSITY OF CALIFORNIA RIVERSIDE · NIH-10499289

This study is looking at new ways to read proteins, which are important for how our genes work in our bodies, and it could help patients by providing better understanding of how protein problems can affect health and lead to new treatments.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA RIVERSIDE (nih funded)
Locations1 site (RIVERSIDE, UNITED STATES)
Trial IDNIH-10499289 on ClinicalTrials.gov

What this research studies

This research focuses on developing new methods for sequencing proteins, which are crucial for understanding how genetic information is translated into functional molecules in the body. By utilizing nanopores and deep-ultraviolet Raman spectroscopy, the project aims to overcome the challenges associated with traditional protein sequencing techniques. Patients may benefit from insights gained about protein structures and their roles in health and disease, potentially leading to new therapeutic approaches. The research will explore how errors in protein synthesis can affect health outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with conditions related to protein synthesis errors or those interested in the molecular basis of their health issues.

Not a fit: Patients with conditions unrelated to protein synthesis or those not interested in molecular biology may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to breakthroughs in understanding protein-related diseases and the development of new treatments.

How similar studies have performed: While protein sequencing has been challenging, advances in related technologies suggest potential for success in this novel approach.

Where this research is happening

RIVERSIDE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.