Investigating plasma proteins in older adults to understand cardiovascular health
Plasma proteomics in CHS and population biology
This study is looking at blood proteins in older adults to better understand heart health and aging, with the hope of finding new treatments that can help improve their well-being.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10439453 on NIH RePORTER |
What this research studies
This research focuses on analyzing plasma proteins in older adults to gain insights into cardiovascular health and aging. By utilizing advanced techniques to measure 1310 different proteins in the blood of 3200 participants from the Cardiovascular Health Study, the project aims to identify biomarkers that could lead to new therapies. The study employs an aptamer-based method, which is highly sensitive and allows for the analysis of low-abundance proteins in a large number of samples. This approach not only enhances our understanding of biological processes but also aims to improve clinical outcomes for older adults.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those participating in the Cardiovascular Health Study.
Not a fit: Patients who are younger than 65 years old or do not have cardiovascular health concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new therapies and improved management strategies for cardiovascular diseases in older adults.
How similar studies have performed: Previous research utilizing omics data has shown promise in identifying health-related biomarkers and developing new treatments, indicating a strong potential for success in this area.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Psaty, Bruce M — University of Washington
- Study coordinator: Psaty, Bruce M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.