Investigating personalized treatments for children with sepsis
Collaborative Pediatric Critical Care Research Network - Clinical Site
This study is looking at how children aged 0-11 with sepsis respond to infections by collecting blood samples, so we can find better ways to help their immune systems fight the illness and improve their chances of recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-10915541 on NIH RePORTER |
What this research studies
This research focuses on children aged 0-11 who are suffering from sepsis, a severe infection that can lead to multiple organ failure. The study involves a large randomized trial where blood samples will be collected from these children to analyze their immune response and inflammation levels. By understanding how well their bodies are fighting the infection, researchers aim to develop personalized immunomodulation therapies that could improve survival rates. The research is conducted at multiple pediatric hospitals, including UPMC Children’s Hospital of Pittsburgh and Mercy Children’s Hospital Kansas City.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 who are diagnosed with sepsis and admitted to participating hospitals.
Not a fit: Patients who are not diagnosed with sepsis or are older than 11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for sepsis in children, potentially saving lives and improving recovery outcomes.
How similar studies have performed: Previous research has shown promise in using personalized medicine approaches for treating sepsis, indicating potential for success in this novel trial.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Carcillo, Joseph a — University of Utah
- Study coordinator: Carcillo, Joseph a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.