Investigating personalized treatments for children with sepsis
Collaborative Pediatric Critical Care Research Network - Clinical Site
['FUNDING_OTHER'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10900565
This study is looking at how children aged 0-11 with sepsis respond to infections by taking blood samples, so we can find better ways to help their immune systems fight off the illness and improve their chances of recovery.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-10900565 on ClinicalTrials.gov |
What this research studies
This research focuses on children aged 0-11 who are experiencing sepsis, a severe infection that can lead to multiple organ failure. The study will involve drawing blood samples from these children to analyze their immune response and inflammation levels. By understanding how well their bodies are fighting the infection, the researchers aim to develop personalized immunomodulation therapies that could improve survival rates. The research is part of a larger collaborative network aimed at enhancing pediatric critical care.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 who are diagnosed with sepsis and admitted to participating hospitals.
Not a fit: Patients who are not diagnosed with sepsis or are older than 11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for children suffering from sepsis, potentially reducing mortality rates.
How similar studies have performed: Other research has shown promise in using personalized immunomodulation approaches for treating sepsis, indicating potential for success in this study.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CARCILLO, JOSEPH A — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: CARCILLO, JOSEPH A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury