Investigating personalized treatment options for Idiopathic Pulmonary Fibrosis using genetic information.
1/2 Prospective tReatment EffiCacy in IPF uSlng genOtype for Nac Selection (PRECISIONS) trial and Molecular Endophenotyping in Idiopathic Pulmonary Fibrosis and Interstitial Lung Diseases study
This study is looking to help people with Idiopathic Pulmonary Fibrosis (IPF) by using their genetic information to find the best treatments for them, so they can get care that’s more personalized and effective.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project ID | NIH-11075126 on NIH RePORTER |
What this research studies
This research focuses on improving the diagnosis and treatment of Idiopathic Pulmonary Fibrosis (IPF) by utilizing genetic information to tailor antifibrotic therapies. By partnering with the Pulmonary Fibrosis Foundation, the study aims to collect and analyze biological samples and patient data to identify genetic variants that influence treatment response. The goal is to move away from a 'one size fits all' approach and develop precision medicine strategies that can better manage this challenging condition. Patients will be involved in a trial that assesses how their genetic makeup can guide more effective treatment options.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Idiopathic Pulmonary Fibrosis who are willing to provide genetic samples and participate in a precision medicine trial.
Not a fit: Patients with other forms of interstitial lung diseases or those not diagnosed with Idiopathic Pulmonary Fibrosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for patients with Idiopathic Pulmonary Fibrosis.
How similar studies have performed: Previous research has shown promise in using genetic information to tailor treatments for various conditions, indicating that this approach could be beneficial for IPF as well.
Where this research is happening
Worcester, United States
- Univ of Massachusetts Med Sch Worcester — Worcester, United States (Active)
Researchers
- Principal investigator: Martinez, Fernando J — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Martinez, Fernando J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.