Investigating persistent kidney swelling in children diagnosed before birth.
The Utah-Cohort Of Postnatally persistent Antenatal Hydronephrosis (U-COPAH)
This study is looking at a kidney condition called postnatally persistent hydronephrosis, which means the swelling seen before birth continues after the baby is born, and it aims to create a helpful tool for doctors to better understand and manage this condition as the child grows.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-10766185 on NIH RePORTER |
What this research studies
This research focuses on postnatally persistent hydronephrosis (PNH), a condition where kidney swelling diagnosed in utero continues after birth. The project aims to develop a standardized management strategy for PNH by creating an ultrasound grading tool that translates complex ultrasound reports into structured data. It will also predict the severity of PNH at two years of age using initial ultrasound and renal scan data, and simulate the natural history of the condition to understand its progression. This approach will help clinicians make informed decisions about patient care.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants and young children diagnosed with hydronephrosis before birth who continue to show symptoms after birth.
Not a fit: Patients without a diagnosis of hydronephrosis or those whose condition resolves immediately after birth may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved management strategies for children with hydronephrosis, enhancing their health outcomes.
How similar studies have performed: Previous research has shown promise in using similar data-driven approaches to improve management strategies for pediatric urologic conditions.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Schaeffer, Anthony J — University of Utah
- Study coordinator: Schaeffer, Anthony J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.