Investigating pain pathways in knee osteoarthritis
Novel models to study dorsal root ganglion neurons in knee osteoarthritis pain
This study is looking at how certain nerve cells in the body are linked to pain in people with knee osteoarthritis, with the goal of finding new and easier ways to help manage that pain.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11193276 on NIH RePORTER |
What this research studies
This research focuses on understanding how specific nerve cells, known as dorsal root ganglion neurons, contribute to pain in knee osteoarthritis. By targeting these neurons, the study aims to develop new pain management strategies that are less invasive and more effective than current treatments. The approach involves identifying the precise populations of neurons involved in transmitting pain signals, which could lead to better therapeutic options for patients suffering from this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 45 years old who are experiencing chronic pain due to knee osteoarthritis.
Not a fit: Patients with knee osteoarthritis who are not experiencing significant pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer pain relief options for patients with knee osteoarthritis.
How similar studies have performed: Previous research has shown promise in targeting specific nerve populations for pain relief, indicating that this approach could be effective.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Brewer, Chelsie L — Stanford University
- Study coordinator: Brewer, Chelsie L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.