Investigating oxygen therapy for eye injuries caused by mustard gas
Official title: Tissue Hypoxia and Topical Oxygen Therapy in Ocular Mustard Gas Injury
Funded at Schepens Eye Research Institute · NIH-10865037 · Data updated 2026-11-12
This study is looking at how exposure to mustard gas can harm your eyes and cause serious problems like vision loss, and it’s testing a new treatment that delivers extra oxygen directly to the eye to help heal those injuries.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Schepens Eye Research Institute NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $296,810 |
| NIH project number | 5R21EY034833-02 |
| Project ID | NIH-10865037 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have experienced ocular injuries due to mustard gas exposure.
✕Less likely to help
Patients with eye injuries from other causes unrelated to mustard gas may not benefit from this research.
What this research studies
This research focuses on the effects of mustard gas exposure on the eyes, which can lead to severe injuries such as corneal defects and blindness. The study aims to understand how tissue hypoxia, or lack of oxygen, contributes to these injuries and explores a new treatment using a specialized oxygen emulsion that delivers high levels of oxygen directly to the eye. By examining the mechanisms of injury and the potential benefits of this therapy, the research seeks to provide a targeted approach to treating mustard gas-related ocular damage.
Why it matters
Potential benefit: If successful, this research could lead to a novel treatment that significantly improves healing and visual outcomes for patients suffering from mustard gas eye injuries.
How similar studies have gone: While the approach of using oxygen therapy for chemical injuries is innovative, similar studies have shown promise in treating other types of tissue hypoxia, suggesting potential for success.
Where this research is happening
-
Schepens Eye Research Institute
Boston, United States Active
Researchers
- Principal investigator: Yin, Jia — Schepens Eye Research Institute
- Study coordinator: Yin, Jia
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.