Investigating ovarian health in women with sickle cell anemia
OVARIAN RESERVE IN POST-MENARCHAL FEMALES WITH SICKLE CELL ANEMIA
This study is looking at how sickle cell anemia and its treatment with hydroxyurea might affect women's ability to have children, helping to provide important information for women with this condition about their reproductive health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10901879 on NIH RePORTER |
What this research studies
This research focuses on understanding how sickle cell anemia (SCA) and its treatment with hydroxyurea may impact ovarian reserve in women. By evaluating the reproductive health of women with SCA, the study aims to identify potential risks associated with fertility and the effects of long-term treatment. The research will involve a detailed assessment of ovarian function and how it relates to the severity of the disease and treatment duration. This information is crucial for guiding reproductive health decisions for women living with SCA.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with sickle cell anemia, particularly those who have been treated with hydroxyurea.
Not a fit: Patients without a diagnosis of sickle cell anemia or those who have not received treatment with hydroxyurea may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide critical insights that help improve fertility management and reproductive health care for women with sickle cell anemia.
How similar studies have performed: Previous research has indicated potential fertility risks associated with sickle cell anemia and its treatments, suggesting that this area of investigation is both relevant and necessary.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Pecker, Lydia — Johns Hopkins University
- Study coordinator: Pecker, Lydia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.