Investigating orexin agonists to help with obesity treatment
Orexin agonists as novel obesity therapeutics
['FUNDING_OTHER'] · MINNEAPOLIS VA MEDICAL CENTER · NIH-10911021
This study is looking at a new treatment for obesity that uses special compounds called orexin agonists to help Veterans burn more energy and manage their weight better, with the hope of finding effective long-term solutions for those struggling with obesity.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MINNEAPOLIS VA MEDICAL CENTER (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-10911021 on ClinicalTrials.gov |
What this research studies
This research focuses on the potential of orexin agonists as a new treatment for obesity, particularly among Veterans. It aims to understand how these compounds can enhance energy expenditure and improve weight management by targeting the orexin neuropeptide system in the brain. The study will involve assessing the effects of orexin on physical activity, energy balance, and overall health outcomes in individuals struggling with obesity. By exploring this novel approach, the research seeks to provide effective long-term solutions for weight maintenance.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults, particularly Veterans, who are struggling with obesity and related health issues.
Not a fit: Patients who are not overweight or obese, or those with conditions that contraindicate the use of orexin agonists, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that help individuals maintain weight loss and improve their overall health.
How similar studies have performed: Previous research has shown promising results with orexin's role in regulating energy expenditure, suggesting potential success for this novel therapeutic approach.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- MINNEAPOLIS VA MEDICAL CENTER — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KOTZ, CATHERINE M — MINNEAPOLIS VA MEDICAL CENTER
- Study coordinator: KOTZ, CATHERINE M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.