Investigating oral treatments for COVID-19 in outpatient settings
ACTIV-6
This study is looking for ways to use safe, existing medications to help treat COVID-19 for people who aren't in the hospital, so if you're dealing with COVID-19, this research might lead to new treatment options for you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10652817 on NIH RePORTER |
What this research studies
This research focuses on developing and testing oral treatments for COVID-19, particularly for patients who are not hospitalized. It aims to create a platform for clinical trials that can quickly evaluate existing medications that have shown promise in treating COVID-19. By repurposing drugs with established safety profiles, the study seeks to provide effective treatment options as the pandemic evolves. Patients will be monitored for safety and efficacy as part of this coordinated effort among leading medical institutions.
Who could benefit from this research
Good fit: Ideal candidates for participation include adults and children aged 0-21 who have tested positive for COVID-19 and are experiencing mild to moderate symptoms.
Not a fit: Patients who are severely ill or require hospitalization for COVID-19 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide new, effective oral treatment options for COVID-19, improving patient outcomes and reducing hospitalizations.
How similar studies have performed: Previous research has successfully repurposed existing medications for other viral infections, indicating potential for success in this approach.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Benjamin, Daniel K. — Duke University
- Study coordinator: Benjamin, Daniel K.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.