Investigating oral HPV and cancer risk in Latin Americans with HIV
Oral HPV Research Among Latin Americans Living with HIV (ORAL - H² Study)
This study is looking at how oral HPV infections might lead to throat cancer in Latin Americans with HIV, and it aims to find ways to help those at higher risk, including checking if a specific vaccine can help prevent this cancer in people who might not usually get vaccinated.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-10906239 on NIH RePORTER |
What this research studies
This research focuses on understanding the link between oral HPV infections and the risk of oropharyngeal cancer (OPC) among Latin Americans living with HIV. The team aims to identify modifiable risk factors and biomarkers that can help pinpoint individuals at higher risk for developing OPC. By examining sexual behaviors and other factors that contribute to HPV persistence, the study seeks to improve prevention strategies and surveillance for those most affected. The research also explores the efficacy of the 9vHPV vaccine in preventing OPC, particularly in populations that may not have access to vaccination.
Who could benefit from this research
Good fit: Ideal candidates for this research are Latin American individuals living with HIV, particularly those aged 65 and older.
Not a fit: Patients who are not living with HIV or who do not have a history of oral HPV infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies and early detection methods for oropharyngeal cancer in high-risk populations.
How similar studies have performed: Previous research has shown promising results in understanding HPV-related cancers, but this specific approach focusing on Latin Americans with HIV is relatively novel.
Where this research is happening
Tampa, United States
- H. Lee Moffitt Cancer Ctr & Res Inst — Tampa, United States (Active)
Researchers
- Principal investigator: Giuliano, Anna R. — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Giuliano, Anna R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.