Investigating oral dysplasia and cancer risk using a new diagnostic tool

Who could benefit from this research

What this research studies

This research focuses on improving the diagnosis and monitoring of oral dysplasia and oral cavity cancers through a novel chairside cytopathology tool. By utilizing advanced microfluidics and artificial intelligence, the study aims to provide a non-invasive method for detecting potentially malignant oral lesions. Patients with a history of oral squamous cell carcinoma or those diagnosed with oral epithelial dysplasia will be monitored to assess the effectiveness of this new diagnostic approach. The goal is to enhance clinical surveillance and improve patient outcomes through timely and accurate diagnosis.

Why it matters

Where this research is happening

• New York University
  New York, United States Active

Researchers

• Principal investigator: Mcdevitt, John T — New York University
• Study coordinator: Mcdevitt, John T

Related research

Other NIH-funded projects on the same topics.

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  Recruiting Phase 2 Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Baltimore, Maryland · NCT07209189

• Sacituzumab govitecan plus cetuximab for recurrent or metastatic head and neck squamous cell cancer

  This trial will test whether combining sacituzumab govitecan with cetuximab works and is safe for people whose head and neck squamous cell cancer has returned or spread after prior immunotherapy.

  Recruiting at 7 sites Phase 2 Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT07063212

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  Recruiting at 4 sites Medical University of South Carolina · St Louis, Missouri and 3 other locations · NCT05793151

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  This study is testing a new surgical method using a special tissue flap to see if it can safely help cancer patients who need reconstruction in their mouth and throat areas.

  Recruiting at 2 sites Institut Claudius Regaud · Montpellier and 3 other locations · NCT05757817

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.