Investigating nutritional and environmental factors linked to nerve damage in Zambia
Community Health and Neuropathy: Nutritional and Environmental Links in Zambia (CHANNELZ)
['FUNDING_OTHER'] · UNIVERSITY OF ROCHESTER · NIH-10893355
This study is looking into what causes nerve damage in people in Zambia, especially those who mainly eat maize and cassava, to see how common it is and what might be contributing to it, while also checking if there are any vitamin deficiencies that could help improve health in the future.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ROCHESTER (nih funded) |
| Locations | 1 site (ROCHESTER, UNITED STATES) |
| Trial ID | NIH-10893355 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the causes of distal symmetric polyneuropathies (DSP) in Zambia, particularly in areas where maize and cassava are staple foods. It aims to assess the prevalence and risk factors for DSP in the population and compare these findings with previous clinic-based data. The study will also evaluate micronutrient deficiencies among individuals with DSP and matched controls, which may help identify potential nutritional interventions. The research is designed to enhance knowledge of how nutrition and environmental factors contribute to nerve damage, ultimately informing future health policies and interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals over 21 years old living in Zambia who are experiencing symptoms of distal symmetric polyneuropathy or have been diagnosed with related conditions.
Not a fit: Patients who do not reside in Zambia or those who are not experiencing symptoms of neuropathy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved nutritional interventions that reduce nerve damage and enhance the quality of life for affected individuals.
How similar studies have performed: Previous research has indicated a high prevalence of distal symmetric polyneuropathies in clinic populations in Zambia, suggesting that this approach may yield valuable insights.
Where this research is happening
ROCHESTER, UNITED STATES
- UNIVERSITY OF ROCHESTER — ROCHESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KVALSUND, MICHELLE POWELL — UNIVERSITY OF ROCHESTER
- Study coordinator: KVALSUND, MICHELLE POWELL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus