Investigating new treatments for obstructive sleep apnea
Project 4
This study is looking at ways to help people with obstructive sleep apnea breathe better at night by improving the muscles that keep their airways open, using mice to find new treatments that could make a real difference for those affected.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10897860 on NIH RePORTER |
What this research studies
This research focuses on obstructive sleep apnea (OSA), a condition that affects many adults and leads to excessive daytime sleepiness and various health issues. The team aims to explore new ways to enhance the function of muscles that keep the airway open during sleep, potentially improving breathing without causing awakenings. By studying specific brain circuits and serotonergic neurons in mice, the researchers hope to identify effective interventions that could lead to better treatment options for patients suffering from OSA.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who suffer from obstructive sleep apnea.
Not a fit: Patients who do not have obstructive sleep apnea or are under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments for obstructive sleep apnea that improve quality of life and reduce health complications.
How similar studies have performed: While there have been advancements in understanding sleep apnea, this approach focusing on specific neural circuits and serotonergic systems is relatively novel.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Vanderhorst, Veronique — Beth Israel Deaconess Medical Center
- Study coordinator: Vanderhorst, Veronique
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.