Investigating new treatments for non-T2 asthma
Official title: Project-002
Funded at University of Washington · NIH-11281357 · Data updated 2026-11-12
This study is looking at how certain viral infections cause extra inflammation in people with a type of asthma that doesn't respond well to usual treatments, and it's for both kids and adults who have this condition, with the hope of finding better ways to help them breathe easier.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | April 25, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $470,231 |
| NIH project number | 5U19AI175089-03 |
| Project ID | NIH-11281357 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include children and adults diagnosed with non-T2 asthma who experience frequent asthma exacerbations.
✕Less likely to help
Patients with T2 asthma, who respond well to existing treatments targeting type-2 inflammation, may not benefit from this research.
What this research studies
This research focuses on understanding the mechanisms behind non-T2 asthma, a type of asthma that does not respond well to standard treatments. By examining airway epithelial cells from both children and adults with and without asthma, the researchers aim to uncover how viral infections trigger excessive inflammation in non-T2 asthma patients. The study will utilize advanced organotypic models to simulate the airway environment and assess immune responses. This approach could lead to the development of more effective therapies for individuals suffering from this condition.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for patients with non-T2 asthma, improving their quality of life and reducing asthma exacerbations.
How similar studies have gone: While there has been significant research on T2 asthma, the specific focus on non-T2 asthma and its unique mechanisms is relatively novel and has not been extensively tested.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Hallstrand, Teal S — University of Washington
- Study coordinator: Hallstrand, Teal S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.