Investigating new treatments for chronic pain and spasticity in veterans
Center for Restoration of Nervous System Function
This study is looking for better, non-addictive ways to help veterans with chronic pain and muscle tightness, while also exploring how genetics might affect their pain experience, especially for those who have lost a limb.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA Connecticut Healthcare System NIH-funded |
| Lab location | 1 site (West Haven, United States) |
| Project ID | NIH-10758400 on NIH RePORTER |
What this research studies
This research focuses on developing effective, non-addictive treatments for chronic pain and spasticity, particularly in veterans. It explores the genetic factors that influence pain resilience and aims to identify druggable targets through patient-specific stem cells. The study also investigates the genetic risk factors associated with phantom limb pain in veterans who have undergone limb amputation. By utilizing advanced techniques like 2-photon microscopy, the research seeks to enhance our understanding of pain mechanisms and improve treatment options.
Who could benefit from this research
Good fit: Ideal candidates for this research include veterans experiencing chronic pain or spasticity, particularly those with a history of limb amputation.
Not a fit: Patients who do not have chronic pain or spasticity, or who are under 21 years old, may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer pain management options for veterans suffering from chronic pain.
How similar studies have performed: Previous research has shown promise in identifying genetic factors related to pain, suggesting that this approach could lead to significant advancements in treatment.
Where this research is happening
West Haven, United States
- VA Connecticut Healthcare System — West Haven, United States (Active)
Researchers
- Principal investigator: Waxman, Stephen — VA Connecticut Healthcare System
- Study coordinator: Waxman, Stephen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.