Investigating new treatments for brain tumors that can cross the blood-brain barrier.
Immune Monitoring and Biospecimen Core
This study is looking for new ways to help treat brain tumors, especially glioblastoma, by figuring out how to get better medicines into the brain, and it involves collecting samples from patients to learn more about how their immune systems respond to the tumors.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10910092 on NIH RePORTER |
What this research studies
This research focuses on developing innovative agents that can effectively cross the blood-brain barrier to treat brain tumors, particularly glioblastoma. The team at the University of California, San Francisco, and Northwestern University will collect and analyze biospecimens from patients and preclinical models to understand immune responses and tumor characteristics. Advanced techniques such as flow cytometry and single-cell RNA sequencing will be employed to ensure high-quality data and insights. The goal is to enhance the effectiveness of treatments for patients with brain tumors through rigorous immune monitoring and biospecimen analysis.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with glioblastoma or other brain tumors who are undergoing treatment.
Not a fit: Patients with brain tumors who are not eligible for clinical trials or those with conditions unrelated to glioblastoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with brain tumors, improving their outcomes and quality of life.
How similar studies have performed: Previous research has shown promise in developing therapies that target brain tumors, but this approach is particularly focused on overcoming the blood-brain barrier, making it a novel endeavor.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Phillips, Joanna — University of California, San Francisco
- Study coordinator: Phillips, Joanna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.