Investigating new treatments for bone cancer in veterans

BLRD Research Career Scientist Award Application

NIH-funded research Veterans Health Administration · NIH-10951545

This study is looking at new ways to help veterans with breast cancer that has spread to their bones, by trying to boost the body's immune response to fight the cancer and reduce bone damage.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVeterans Health Administration NIH-funded
Lab location1 site (Nashville, United States)
Project IDNIH-10951545 on NIH RePORTER

What this research studies

This research focuses on developing innovative therapies to combat bone metastatic breast cancer, particularly in veterans who are disproportionately affected by this condition. The principal investigator, Dr. Rhoades, aims to reprogram tumor-associated macrophages to enhance anti-tumor immune responses, thereby reducing bone destruction caused by tumors. The study will explore the interactions between tumors and bone, seeking to improve diagnosis and treatment outcomes for patients. By leveraging her extensive experience and previous funding, Dr. Rhoades hopes to enhance the quality of life and survival rates for veterans suffering from these aggressive cancers.

Who could benefit from this research

Good fit: Ideal candidates for this research are veterans diagnosed with bone metastatic breast cancer or those at high risk for developing this condition.

Not a fit: Patients who do not have a history of bone metastatic breast cancer or are not veterans may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments that improve survival and quality of life for veterans with bone metastatic breast cancer.

How similar studies have performed: Previous research has shown promise in reprogramming immune cells to fight cancer, indicating that this approach may lead to significant advancements in treatment.

Where this research is happening

Nashville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions anti-cancer researchanti-cancer therapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.