Investigating new treatments for age-related macular degeneration

Retinoid cycles and retinal disease treatment

['FUNDING_OTHER'] · VETERANS HEALTH ADMINISTRATION · NIH-11061800

This study is looking at how certain vitamin A-related compounds might help improve vision for older adults with age-related macular degeneration (AMD), and it aims to find new treatments that could make life better for those dealing with this condition.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorVETERANS HEALTH ADMINISTRATION (nih funded)
Locations1 site (LONG BEACH, UNITED STATES)
Trial IDNIH-11061800 on ClinicalTrials.gov

What this research studies

This research focuses on age-related macular degeneration (AMD), a leading cause of vision loss in older adults. The team aims to explore the role of retinoids, which are compounds related to vitamin A, in treating this condition. By studying how these compounds function at a cellular level, the researchers hope to develop new therapies that could improve vision and quality of life for those affected by AMD. The research involves both laboratory studies and the use of advanced mouse models to better understand the disease mechanisms.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 65 and older who are experiencing symptoms of age-related macular degeneration.

Not a fit: Patients under the age of 65 or those without age-related macular degeneration may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective treatments that restore or preserve vision for individuals suffering from age-related macular degeneration.

How similar studies have performed: Previous research has shown promise in using retinoid modulation for treating retinal diseases, indicating a potential for success in this approach.

Where this research is happening

LONG BEACH, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.