Investigating new treatment strategies for cervical cancer
Research Project Cervical Cancer
This study is looking at how certain immune cells in the body affect the treatment of locally advanced cervical cancer, with the goal of finding better ways to help patients respond to radiation therapy and improve their chances of recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10912702 on NIH RePORTER |
What this research studies
This research focuses on improving treatment outcomes for patients with locally advanced cervical cancer, which currently has a high failure rate with standard therapies. The study examines the role of tumor-associated macrophages in the tumor microenvironment and how they interact with cancer cells after radiation therapy. By analyzing these interactions, the research aims to identify metabolic changes that could be targeted to enhance anti-tumor immunity and improve patient responses to treatment. Patients may be involved in trials that explore new therapeutic approaches based on these findings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with locally advanced cervical cancer who are undergoing standard treatment.
Not a fit: Patients with early-stage cervical cancer or those who have already received multiple lines of treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for cervical cancer, potentially reducing recurrence rates and improving survival.
How similar studies have performed: Previous research has shown promising results in targeting tumor-associated macrophages to enhance cancer treatment, suggesting that this approach may be effective.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Schwarz, Julie Kristina — Washington University
- Study coordinator: Schwarz, Julie Kristina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.