NIH-funded research NIH-funded research

Investigating new therapies for rheumatoid arthritis in veterans

Official title: BLRD Research Career Scientist Award Application

Funded at Jesse Brown VA Medical Center · NIH-10951542 · Data updated 2026-11-12

This study is looking at how rheumatoid arthritis affects veterans, aiming to find out what causes joint pain and damage so that new treatments can be developed to help improve their quality of life.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJesse Brown VA Medical Center
NIH-funded
Lab location1 site (Chicago, United States)
Project startOctober 1, 2023
Project endSeptember 30, 2028
Funding year2025
NIH project number5IK6BX006474-02
Project IDNIH-10951542 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include veterans diagnosed with rheumatoid arthritis, particularly those who have not responded well to existing treatments.

Less likely to help

Patients with rheumatoid arthritis who are already effectively managing their condition with current therapies may not receive additional benefit from this research.

What this research studies

This research focuses on rheumatoid arthritis (RA), a common autoimmune disease affecting many veterans. The study aims to identify mechanisms that lead to joint inflammation and bone erosion, which are critical in understanding RA progression. By exploring the role of specific molecules in the disease process, the research seeks to develop new therapies that could improve treatment outcomes for patients. The findings could lead to better management of RA symptoms and enhance the quality of life for those affected.

Why it matters

Potential benefit: If successful, this research could lead to new therapies that significantly improve the management of rheumatoid arthritis and enhance the quality of life for patients.

How similar studies have gone: Previous research has shown promise in targeting similar pathways in autoimmune diseases, indicating potential for success in this novel approach.

Where this research is happening

  • Jesse Brown VA Medical Center
    Chicago, United States
    Active

Researchers

  • Principal investigator: Shahrara, Shiva — Jesse Brown VA Medical Center
  • Study coordinator: Shahrara, Shiva

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.