Investigating new non-addictive treatments for pain management
EPPIC-Net Pain Research - Application for Clinical Trial and Related Activities (OT2)
This study is looking for new, non-addictive ways to help people with pain, like those with knee osteoarthritis, so they can find relief without relying on opioids.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10818656 on NIH RePORTER |
What this research studies
This research focuses on developing and testing non-addictive pain treatments to address the opioid crisis, particularly for patients suffering from acute and chronic pain. It is part of the Early Phase Pain Investigation Clinical Network (EPPIC-Net) and aims to conduct early phase clinical trials to evaluate the safety and efficacy of novel therapeutics and devices. Patients with specific pain conditions, such as knee osteoarthritis, will be enrolled in trials to assess new treatment options that could reduce reliance on opioids. The research also includes in-depth studies of patient characteristics and biomarkers to better understand pain management needs.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals suffering from moderate to severe knee osteoarthritis pain or other specific pain conditions.
Not a fit: Patients who do not have pain conditions or those who are not seeking alternative pain management options may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide patients with safer, non-addictive alternatives for pain relief.
How similar studies have performed: Previous research has shown promise in developing non-addictive pain treatments, but this approach is part of a larger initiative to address the opioid crisis and may yield novel insights.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Fava, Maurizio — Massachusetts General Hospital
- Study coordinator: Fava, Maurizio
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.