NIH-funded research NIH-funded research

Investigating neuroimaging and biomarkers in older adults with and without COVID-19

Official title: Neuroimaging Core

Funded at University of Texas Hlth Science Center · NIH-10907424 · Data updated 2026-11-12

This study is looking for 4,300 people aged 60 and older to help us understand how COVID-19 might affect brain health, especially in relation to conditions like Alzheimer's, by comparing those who had COVID-19 with those who didn't over three years.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Texas Hlth Science Center
NIH-funded
Lab location1 site (San Antonio, United States)
Project startAugust 15, 2023
Project endJuly 31, 2028
Funding year2024
Award (this year)$929,085
NIH project number5U19AG076581-02
Project IDNIH-10907424 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals aged 60 and older, particularly those with a history of COVID-19 infection.

Less likely to help

Patients who are younger than 60 years old or do not have a history of COVID-19 may not benefit from this research.

What this research studies

This research involves a large-scale study that will enroll 4,300 individuals aged 60 and older to examine the effects of COVID-19 on brain health. Participants will be divided into two groups: those with a history of COVID-19 and those without. Over a period of three years, participants will undergo neuroimaging and clinical assessments at three different time points to gather data on brain structure and function, as well as genetic and biomarker information. The study aims to enhance our understanding of how COVID-19 may impact neurodegenerative conditions like Alzheimer's disease.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of brain health in older adults, particularly in relation to COVID-19.

How similar studies have gone: Previous research has shown success in using neuroimaging to study Alzheimer's disease and related conditions, making this approach promising.

Where this research is happening

  • University of Texas Hlth Science Center
    San Antonio, United States
    Active

Researchers

  • Principal investigator: Fox, Peter Thornton — University of Texas Hlth Science Center
  • Study coordinator: Fox, Peter Thornton

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.