Investigating nerve degeneration in dogs to understand human nerve diseases
Official title: Establishing the neuropathologic and molecular features of a spontaneous canine model of peripheral neuropathy
Funded at University of Wisconsin-Madison · NIH-11070900 · Data updated 2026-11-12
This study is looking at a nerve condition that affects both dogs and people, focusing on Labrador Retrievers with a specific type of nerve problem, to learn more about it and potentially help find better treatments for everyone affected.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | January 15, 2025 |
| Project end | January 14, 2031 |
| Funding year | 2025 |
| Award (this year) | $38,258 |
| NIH project number | 1F30NS137752-01A1 |
| Project ID | NIH-11070900 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include dogs, particularly Labrador Retrievers, that exhibit symptoms of late-onset peripheral neuropathy.
✕Less likely to help
Patients who are not dogs or do not have hereditary peripheral neuropathies may not receive any benefit from this research.
What this research studies
This research focuses on hereditary peripheral neuropathies (HPNs), which cause nerve degeneration in both dogs and humans. By studying Labrador Retrievers with late-onset peripheral neuropathy, researchers aim to uncover the neuropathologic and molecular features of this condition. The study will involve examining the structure of the neuromuscular junction and peripheral nerves in affected dogs, which may provide insights applicable to human HPNs. The findings could help establish a canine model that can be used for future research and potential treatments.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of peripheral neuropathies and pave the way for developing effective treatments for both dogs and humans.
How similar studies have gone: Previous research has successfully utilized canine models to study human diseases, indicating that this approach has potential for yielding valuable insights.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Anderson, Ryan S — University of Wisconsin-Madison
- Study coordinator: Anderson, Ryan S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.