Investigating natural products for cancer and antibiotic treatments
Synthetic and translational studies of antitumor and antimicrobial natural products.
This study is looking at how natural compounds might help treat tough bacterial infections and different kinds of cancer, with the hope of creating new and better treatment options for patients who need them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11082286 on NIH RePORTER |
What this research studies
This research focuses on understanding how certain natural compounds can be used to treat drug-resistant bacterial infections and various types of cancer. The team is working on synthesizing specific molecules, such as lomaiviticin A and gukulenin A, which have shown promise in inhibiting cancer cell growth and fighting bacterial infections. By exploring the structure and function of these compounds, the researchers aim to develop effective therapies that can overcome current treatment challenges. Patients may benefit from new treatment options that are more effective against resistant strains of bacteria and cancer cells.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients with drug-resistant bacterial infections or those diagnosed with specific types of cancer.
Not a fit: Patients with non-resistant infections or cancers that are not targeted by the compounds being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new and more effective treatments for patients suffering from drug-resistant infections and cancer.
How similar studies have performed: Other research has shown promise in using natural products for cancer and antimicrobial therapies, indicating potential for success in this area.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Herzon, Seth B. — Yale University
- Study coordinator: Herzon, Seth B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.